{"product_id":"mouse-cathepsin-l1-ctsl1-elisa-kit-96t","title":"Mouse Cathepsin L1, CTSL1 ELISA Kit , 96T","description":"\u003cp\u003eThiol protease important for the overall degradation of proteins in lysosomes (Probable). Involved in the solubilization of cross-linked TG\/thyroglobulin and in the subsequent release of thyroid hormone thyroxine (T4) by limited proteolysis of TG\/thyroglobulin in the thyroid follicle lumen (PubMed: 12782676). In neuroendocrine chromaffin cells secretory vesicles, catalyzes the prohormone proenkephalin processing to the active enkephalin Peptide neurotransmitter (PubMed: 12869695). In thymus, regulates CD4(+) T cell positive selection by generating the major histocompatibility complex class II (MHCII) bound Peptide ligands presented by cortical thymic epithelial cells (PubMed: 12021314). Also mediates invariant chain processing in cortical thymic epithelial cells (PubMed: 9545226). Major elastin-degrading enzyme at neutral pH. Accumulates as a mature and active enzyme in the extracellular space of antigen presenting cells (APCs) to regulate degradation of the extracellular matrix in the course of inflammation (PubMed: 12417635). Secreted form generates endostatin from COL18A1 (PubMed: 10716919). Critical for cardiac morphology and function (PubMed: 11972068). Plays an important role in hair follicle morphogenesis and cycling, as well as epidermal differentiation (PubMed: 12163394). Required for maximal stimulation of steroidogenesis by TIMP1 (By similarity).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592801333621,"sku":"BT-E1911Mo-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/mouse-cathepsin-l1-ctsl1-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}