BT LAB

Artikelnummer: BT-E1950Mo-96T

Mouse Coiled-coil Domain-containing Protein 134, CCDC134 ELISA Kit , 96T

In extracellular secreted form, promotes proliferation and activation of CD8(+) T cells, suggesting a cytokine-like function. Enhances cytotoxic anti-tumor activity of CD8(+) T cells. May inhibit ERK and JNK signaling activity. May suppress cell migration and invasion activity, via its effects on ERK and JNK signaling. In the nucleus, enhances stability of the PCAF histone acetyltransferase (HAT) complex member TADA2A and thus promotes PCAF-mediated H3K14 and H4K8 HAT activity. May inhibit TADA2A-mediated TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity. May also promote TADA2A-mediated XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Sensitivity:0.054ng/mL

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Application:ELISA

Detection Target:CCDC134

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Detection Range: 0.1-38ng/mL

Research Areas:Signal Transduction

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Reactivity:Mouse

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Test Principle:Sandwich

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Assay Time:1h 30m

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