{"product_id":"mouse-lymphoid-enhancer-binding-factor-1-lef1-elisa-kit-96t","title":"Mouse Lymphoid Enhancer-binding Factor 1, LEF1 ELISA Kit, 96T","description":"\u003cp\u003eTranscription factor that binds DNA in a sequence-specific manner (By similarity). Participates in the Wnt signaling pathway (PubMed: 11445543). Activates transcription of target genes in the presence of CTNNB1 and EP300 (PubMed: 12446687). PIASG antagonizes both Wnt-dependent and Wnt-independent activation by LEF1 (PubMed: 11731474). TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by LEF1 and CTNNB1 (By similarity). Regulates T-cell receptor alpha enhancer function (By similarity). Required for IL17A expressing gamma-delta T-cell maturation and development, via binding to regulator loci of BLK to modulate expression (PubMed: 23562159). May play a role in hair cell differentiation and follicle morphogenesis (PubMed: 11445543).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592831086965,"sku":"BT-E2223Mo-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/mouse-lymphoid-enhancer-binding-factor-1-lef1-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}