{"product_id":"mouse-polycomb-complex-protein-bmi-1-bmi-1-elisa-kit-96t","title":"Mouse Polycomb Complex Protein Bmi-1, BMI-1 ELISA Kit, 96T","description":"\u003cp\u003eComponent of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. The complex composed of RNF2, UB2D3 and BMI1 binds nucleosomes, and has activity only with nucleosomal histone H2A. In the PRC1-like complex, regulates the E3 ubiquitin-protein ligase activity of RNF2\/RING2 (By similarity).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592806281589,"sku":"BT-E2018Mo-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/mouse-polycomb-complex-protein-bmi-1-bmi-1-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}