{"product_id":"mouse-protein-o-glucosyltransferase-1-poglut1-elisa-kit-96t","title":"Mouse Protein O-Glucosyltransferase 1, POGLUT1 ELISA Kit, 96T","description":"\u003cp\u003eDual specificity glycosyltransferase that catalyzes the transfer of glucose and xylose from UDP-glucose and UDP-xylose, respectively, to a serine residue found in the consensus sequence of C-X-S-X-P-C (PubMed: 21949356, PubMed: 26496195). Specifically targets extracellular EGF repeats of protein such as CRB2, F7, F9 and NOTCH2 (PubMed: 21949356, PubMed: 26496195). Acts as a positive regulator of Notch signaling by mediating O-glucosylation of Notch, leading to regulate muscle development (By similarity). Notch glucosylation does not affect Notch ligand binding (By similarity). Required during early development to promote gastrulation: acts by mediating O-glucosylation of CRB2, which is required for CRB2 localization to the cell membrane (PubMed: 26496195).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592773939573,"sku":"BT-E0720Mo-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/mouse-protein-o-glucosyltransferase-1-poglut1-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}