{"product_id":"mouse-protein-wnt-5a-wnt5aelisa-kit-96t","title":"Mouse Protein Wnt-5A, WNT5AELISA Kit , 96T","description":"\u003cp\u003eLigand for members of the frizzled family of seven transmembrane receptors (PubMed: 17117926). Can activate or inhibit canonical Wnt signaling, depending on receptor context (PubMed: 16602827). In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression (PubMed: 16602827). Suppression of the canonical pathway allows chondrogenesis to occur and inhibits tumor formation. Stimulates cell migration (PubMed: 17117926). Decreases proliferation, migration, invasiveness and clonogenicity of carcinoma cells and may act as a tumor suppressor. Mediates motility of melanoma cells (By similarity). Required during embryogenesis for extension of the primary anterior-posterior axis and for outgrowth of limbs and the genital tubercle (PubMed: 10021340). Inhibits type II collagen expression in chondrocytes (By similarity).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592786260341,"sku":"BT-E1496Mo-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/mouse-protein-wnt-5a-wnt5aelisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}