{"product_id":"mouse-runt-related-transcription-factor-2-runx2-elisa-kit-96t","title":"Mouse Runt-related Transcription Factor 2, RUNX2 ELISA Kit, 96T","description":"\u003cp\u003eTranscription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. Inhibits KAT6B-dependent transcriptional activation (By similarity). In osteoblasts, supports transcription activation: synergizes with SPEN\/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592849043829,"sku":"BT-E2438Mo-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/mouse-runt-related-transcription-factor-2-runx2-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}