{"product_id":"psk2-polyclonal-antibody-20ul","title":"PSK2 Polyclonal Antibody, 20ul","description":"\u003cp\u003eTAK1 is a mitogen-activated protein kinase kinase kinase that can be activated by TGF-β, bone morphogenetic protein and other cytokines including IL-1. In vivo activation of TAK1 requires association with TAK1 binding protein 1 (TAB1), which triggers phosphorylation of TAK1. Another adaptor protein, TAB2, links TAK1 with TRAF6 and mediates TAK1 activation upon IL-1 stimulation. Once activated, TAK1 phosphorylates MAPK kinases MKK4 and MKK3\/6, which activate p38 MAPK and JNK, respectively. In addition, TAK1 activates the NF-κB pathway by interacting with TRAF6 and phosphorylating the NF-κB inducing kinase (NIK).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56508432449909,"sku":"BT-AP07455-20ul","price":97.2,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_3.jpg?v=1766971577","url":"https:\/\/www.labcart.com\/de\/products\/psk2-polyclonal-antibody-20ul","provider":"LabCart Life Science","version":"1.0","type":"link"}