{"product_id":"pxr-polyclonal-antibody-50ul","title":"PXR Polyclonal Antibody, 50ul","description":"\u003cp\u003eThis gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized. \u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56515961323893,"sku":"BT-AP13418-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/pxr-polyclonal-antibody-50ul","provider":"LabCart Life Science","version":"1.0","type":"link"}