{"product_id":"rag-2-monoclonal-antibody-100ul","title":"RAG-2 Monoclonal Antibody, 100ul","description":"\u003cp\u003eThis gene encodes a protein that is involved in the initiation of V(D)J recombination during B and T cell development. This protein forms a complex with the product of the adjacent recombination activating gene 1, and this complex can form double-strand breaks by cleaving DNA at conserved recombination signal sequences. The recombination activating gene 1 component is thought to contain most of the catalytic activity, while the N-terminal of the recombination activating gene 2 component is thought to form a six-bladed propeller in the active core that serves as a binding scaffold for the tight association of the complex with DNA. A C-terminal plant homeodomain finger-like motif in this protein is necessary for interactions with chromatin components, specifically with histone H3 that is trimethylated at lysine 4. Mutations in this gene cause Omenn syndrome, a form of severe combined immunodef\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56514662007157,"sku":"BT-MCA1090-100ul","price":270.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_6.jpg?v=1768209536","url":"https:\/\/www.labcart.com\/de\/products\/rag-2-monoclonal-antibody-100ul","provider":"LabCart Life Science","version":"1.0","type":"link"}