{"product_id":"rat-myelin-associated-glycoprotein-mag-elisa-kit-96t","title":"Rat Myelin Associated Glycoprotein, MAG ELISA Kit, 96T","description":"\u003cp\u003eAdhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2 (PubMed: 8995428, PubMed: 9298990). Not required for initial myelination, but seems to play a role in the maintenance of normal axon myelination. Protects motoneurons against apoptosis, also after injury; protection against apoptosis is probably mediated via interaction with neuronal RTN4R and RTN4RL2. Required to prevent degeneration of myelinated axons in adults; this probably depends on binding to gangliosides on the axon cell membrane (By similarity). Negative regulator of neurite outgrowth; in dorsal root ganglion neurons the inhibition is mediated primarily via binding to neuronal RTN4R or RTN4RL2 and to a lesser degree via binding to neuronal gangliosides (PubMed: 17640868). In cerebellar granule cells the inhibition is mediated primarily via binding to neuronal gangliosides (PubMed: 17640868). In sensory neurons, inhibition of neurite extension depends only partially on RTN4R, RTN4RL2 and gangliosides (PubMed: 19367338). Inhibits axon longitudinal growth (PubMed: 9298990). Inhibits axon outgrowth by binding to RTN4R (By similarity). Preferentially binds to alpha-2,3-linked sialic acid (PubMed: 8995428). Binds ganglioside Gt1b (PubMed: 8995428).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592911761781,"sku":"BT-E1102Ra-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/rat-myelin-associated-glycoprotein-mag-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}