{"product_id":"rb3-polyclonal-antibody-20ul","title":"RB3 Polyclonal Antibody, 20ul","description":"\u003cp\u003eRB3 (Stathmin-4), encoded by STMN4 gene, is a neuron-specific homologue of the SCG10\/stathmin family proteins, possessing a unique N-terminal membrane-associated domain and the stathmin-like domain at the C terminus, which promotes microtubule (MT) catastrophe and\/or tubulin sequestering. Stathmin is a ubiquitous cytosolic phosphoprotein, preferentially expressed in the nervous system, and described as a relay integrating diverse intracellular signaling pathways. RB3 is consistently up-regulated in differentiated neuroblastoma cells, and stable expression of transfected RB3 could induce differentiation, suggesting a role of RB3 during neuroblastoma differentiation. Moreover, increased RB3 is a unique response protein in the stathmin-related proteins following optical nerve axotomy and RB3 may be a critical target for neurodegenerative diseases.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56508441526645,"sku":"BT-AP07697-20ul","price":97.2,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_3.jpg?v=1766971577","url":"https:\/\/www.labcart.com\/de\/products\/rb3-polyclonal-antibody-20ul","provider":"LabCart Life Science","version":"1.0","type":"link"}