BT LAB

Artikelnummer: BT-AP13703-100ul

RGMC Polyclonal Antibody, 100ul

The product of this gene is involved in iron metabolism. It may be a component of the signaling pathway which activates hepcidin or it may act as a modulator of hepcidin expression. It could also represent the cellular receptor for hepcidin. Two uORFs in the 5' UTR negatively regulate the expression and activity of the encoded protein. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. Defects in this gene are the cause of hemochromatosis type 2A, also called juvenile hemochromatosis (JH). JH is an early-onset autosomal recessive disorder due to severe iron overload resulting in hypogonadotrophic hypogonadism, hepatic fibrosis or cirrhosis and cardiomyopathy, occurring typically before age of 30.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Concentration:1 mg/ml

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Storage:-20°C for 1 year

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Features and Capabilities

Application:WB, ELISA

Detection Target:HFE2

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Research Areas:Metabolism; Signal transduction; Developmental biology; Neuroscience; Stem cells; Cardiovascular

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Reactivity:Human, Rat, Mouse

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Clonality:Polyclonal

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Formulation:Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

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