{"product_id":"ripk1-polyclonal-antibody-50ul","title":"RIPK1 Polyclonal Antibody, 50ul","description":"\u003cp\u003eCatalytic activity:ATP + a protein = ADP + a phosphoprotein.,Promotes apoptosis and activation of NF-kappa-B. Required for TNFRSF1A mediated activation of NF-kappa-B.,PTM:Autophosphorylated on serine and threonine residues.,PTM:Proteolytically cleaved by caspase-8 during TNF-induced apoptosis. Cleavage abolishes NF-kappa-B activation and enhances pro-apototic signaling through the TRADD-FADD interaction.,Belongs to the protein kinase superfamily. TKL Ser\/Thr protein kinase family.,Contains 1 death domain.,Contains 1 protein kinase domain.,subunit:Binds to the death domain of TNFRSF6 and TRADD. Is recruited by TRADD to TNFRSF1A in a TNF-dependent process. Binds RIPK3, UBCE7IP1 isoform 3 (ZIN), EGFR, IKBKG, TRAF1, TRAF2 and TRAF3. Interacts with BNLF1. Interacts with SQSTM1 upon TNF-alpha stimulation. May interacts with MAVS\/IPS1.,\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56515973808501,"sku":"BT-AP13817-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/ripk1-polyclonal-antibody-50ul","provider":"LabCart Life Science","version":"1.0","type":"link"}