{"product_id":"rpa32phospho-thr21-polyclonal-antibody-50ul","title":"RPA32(Phospho Thr21) Polyclonal Antibody, 50ul","description":"\u003cp\u003eRequired for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions.,PTM:Phosphorylated in a cell-cycle-dependent manner (from the S phase until mitosis). Phosphorylated by ATR upon DNA damage, which promotes its translocation to nuclear foci. Can be phosphorylated in vitro by PRKDC\/DNA-PK in the presence of Ku and DNA, and by CDC2.,subcellular location:Also present in PML nuclear bodies. Redistributes to discrete nuclear foci upon DNA damage.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Binds to SERTAD3\/RBT1. Interacts with TIPIN.,\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56515982590325,"sku":"BT-AP13897-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/rpa32phospho-thr21-polyclonal-antibody-50ul","provider":"LabCart Life Science","version":"1.0","type":"link"}