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Artikelnummer: E-AB-92158_60μL-ES
SCAF8 Polyclonal Antibody, 60 μL
Anti-terminator protein required to prevent early mRNA termination during transcription. Together with SCAF4, acts by suppressing the use of early, alternative poly(A sites, thereby preventing the accumulation of non-functional truncated proteins. Mechanistically, associates with the phosphorylated C-terminal heptapeptide repeat domain (CTD of the largest RNA polymerase II subunit (POLR2A, and subsequently binds nascent RNA upstream of early polyadenylation sites to prevent premature mRNA transcript cleavage and polyadenylation. Independently of SCAF4, also acts as a positive regulator of transcript elongation.
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Produktspezifikation
Grundlegende Informationen
Marken: Elabscience
Versand: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Speicher: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Haltbarkeit: 12 months
Herkunftsort: China
Technical Specifications
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Concentration:1mg/mL
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Calculated Molecular Weight:140kDa/147kDa
Observed Molecular Weight:170KDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:140kDa/147kDa
Dilution:WB 1:500-1:1000
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Konzentration: 1mg/mL
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