- Specification
- Downloads
- Reviews
€288,00
ADD TO CART
Artikelnummer: E-AB-15842_120μL-ES
SHH Polyclonal Antibody, 120 μL
This gene encodes a protein that is instrumental in patterning the early embryo. It has been implicated as the key inductive signal in patterning of the ventral neural tube, the anterior-posterior limb axis, and the ventral somites. Of three human proteins showing sequence and functional similarity to the sonic hedgehog protein of Drosophila, this protein is the most similar. The protein is made as a precursor that is autocatalytically cleaved; the N-terminal portion is soluble and contains the signalling activity while the C-terminal portion is involved in precursor processing. More importantly, the C-terminal product covalently attaches a cholesterol moiety to the N-terminal product, restricting the N-terminal product to the cell surface and preventing it from freely diffusing throughout the developing embryo. Defects in this protein or in its signalling pathway are a cause of holoprosencephaly (HPE), a disorder in which the developing forebrain fails to correctly separate into right and left hemispheres. HPE is manifested by facial deformities.
- Regulärer Preis
- €288,00 EUR
- Verkaufspreis
- €288,00 EUR
- Regulärer Preis
-
ADD TO CART
Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
Warranty:
Safety Performance:
Protection Class:
Sterile Status:
Reconstitution:
Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Battery:
Battery Service Life:
Component:
Technical Specifications
Capacity:
Concentration:0.8 mg/mL
Dimension [D×W×H]:
Diameter:
Length:
Width:
High:
Volume:
Volume Range:
Speed:
Speed Range:
Max.Speed:
Max. RCF:
Temperature Range:
Operating Temperature Range:
Permissible Ambient Temperature :
Permissible Relative Humidity:
Input voltage:
Power Requirements:
Voltage/Frequency:
Sensitivity:
Specificity:
Precision:
Speed Accuracy:
Volume Accuracy:
Particle Size:
Pore Size:
Binding Capacity:
Calculated Molecular Weight:
Observed Molecular Weight:
Purity:
Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Random Error:
Acceleration/Braking time:
Aspiration Speed:
Calculated Molecular Weight:
Dilution:IHC 1:50-1:100
Driving Motor DC motor:
Em:
Ex:
Endotoxin:
Flow rate [liquid]:
Features and Capabilities
Application:IHC
Detection Target:
Detection Type:
Detection Range:
Research Areas:Cancer;Epigenetics and Nuclear Signaling;Metabolism;Developmental Biology;Stem Cells
Species Reactivity:Human;Mouse;Rat
Reactivity:
Target Synonym:HHG 1;HHG-1;HHG1;HLP 3;HLP3;Holoprosencephaly 3;HPE 3;HPE3;MCOPCB5;shh;SHH;SMMC I;SMMCI;Sonic Hedgehog (Drosophila) homolog;sonic hedgehog homolog (Drosophila);Sonic hedgehog homolog;Sonic hedgehog protein;Sonic hedgehog protein C-product;TPT;TPTPS
Test Principle:
Quantitative/Qualitative :
Result Type:
Materials :
Assay Time:
Autoclave component:
Available Rotor Adapters:
Binding Capacity:
Bio-activity:
Bottom Shape:
Bottom Type:
Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Cap Color:
Clonality:Polyclonal
Conjugation:Unconjugated
Coupled Ligand:
Cover Type:
Detection Instrument :
Dispensing Speed:
Display:
Form:
Formulation:
Graduation:
Growth Area:
Powered by Bioz