{"product_id":"srebp-1phospho-ser439-polyclonal-antibody-20ul","title":"SREBP-1(Phospho Ser439) Polyclonal Antibody, 20ul","description":"\u003cp\u003eThis gene encodes a transcription factor that binds to the sterol regulatory element-1 (SRE1)| which is a decamer flanking the low density lipoprotein receptor gene and some genes involved in sterol biosynthesis. The protein is synthesized as a precursor that is attached to the nuclear membrane and endoplasmic reticulum. Following cleavage| the mature protein translocates to the nucleus and activates transcription by binding to the SRE1. Sterols inhibit the cleavage of the precursor| and the mature nuclear form is rapidly catabolized| thereby reducing transcription. The protein is a member of the basic helix-loop-helix-leucine zipper (bHLH-Zip) transcription factor family. This gene is located within the Smith-Magenis syndrome region on chromosome 17. \u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56508817703285,"sku":"BT-AP08022-20ul","price":97.2,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_3.jpg?v=1766971577","url":"https:\/\/www.labcart.com\/de\/products\/srebp-1phospho-ser439-polyclonal-antibody-20ul","provider":"LabCart Life Science","version":"1.0","type":"link"}