BT LAB

Artikelnummer: BT-AP12887-50ul

STRAB Rabbit Polyclonal Antibody, 50ul

This gene encodes a protein that belongs to the serine/threonine protein kinase STE20 subfamily. One of the active site residues in the protein kinase domain of this protein is altered| and it is thus a pseudokinase. This protein is a component of a complex involved in the activation of serine/threonine kinase 11| a master kinase that regulates cell polarity and energy-generating metabolism. This complex regulates the relocation of this kinase from the nucleus to the cytoplasm| and it is essential for G1 cell cycle arrest mediated by this kinase. The protein encoded by this gene can also interact with the X chromosome-linked inhibitor of apoptosis protein| and this interaction enhances the anti-apoptotic activity of this protein via the JNK1 signal transduction pathway. Two pseudogenes| located on chromosomes 1 and 7| have been found for this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Product Specification

Basic Information

Brands:BT LAB

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Place of Origin:China

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Concentration:1 mg/ml

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Storage:-20°C for 1 year

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Application:WB

Detection Target:STRADB

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Research Areas:Signal transduction; Metabolism; Cell biology

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Reactivity:Human, Mouse

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Clonality:Polyclonal

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Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

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