{"product_id":"top2aphospho-ser1213-rabbit-polyclonal-antibody-50ul","title":"TOP2A(Phospho Ser1213) Rabbit Polyclonal Antibody, 50ul","description":"\u003cp\u003eCatalytic activity:ATP-dependent breakage| passage and rejoining of double-stranded DNA.|enzyme regulation:Specifically inhibited by the intercalating agent amsacrine.|Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.|miscellaneous:Eukaryotic topoisomerase I and II can relax both negative and positive supercoils| whereas prokaryotic enzymes relax only negative supercoils.|PTM:Phosphorylation has no effect on Catalytic activity.|Belongs to the type II topoisomerase family.|subcellular location:Generally located in the nucleoplasm.|subunit:Homodimer. Interacts with COPS5.|\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56515606249845,"sku":"BT-AP13123-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/de\/products\/top2aphospho-ser1213-rabbit-polyclonal-antibody-50ul","provider":"LabCart Life Science","version":"1.0","type":"link"}