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Artikelnummer: E-AB-53198_200μL-ES
VGLL1 Polyclonal Antibody, 200 μL
The protein encoded by this gene binds proteins of the TEA domain family of transcription factors (TEFs) through the Vg (vestigial) homology region found in its N-terminus. It may thus function as a specific coactivator for the mammalian TEFs. TDU interacted directly with the TEA domain family member, TEF1, and deletion of the Vg homology region abolished the interaction. The TDU-TEF1 dimer activated a reporter plasmid, and expression of TDU in Drosophila rescued loss of Vg function. The interaction was stronger in cardiac myocytes, suggesting a myocyte-specific factor may participate in the interaction. Vgll1 was weakly active in driving expression of a reporter gene from the mouse skeletal muscle alpha-actin promoter, and Vgll1 could partially reverse the inhibitory effect of TEF1 in this assay.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Calculated Molecular Weight:29 kDa
Observed Molecular Weight:Refer to figures
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:29 kDa
Dilution:WB 1:2000-1:10000
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Application:WB
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Research Areas:Epigenetics and Nuclear Signaling
Species Reactivity:Human
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Target Synonym:Protein TONDU;TDU;TONDU;Transcription cofactor vestigial like protein 1;Transcription cofactor vestigial-like protein 1;Vestigial like 1;vestigial like 1 homolog (Drosophila);Vgl-1;VGL1;Vgll1;VGLL1
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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
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Conjugation:Unconjugated
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