{"product_id":"wrnphospho-ser1141-polyclonal-antibody-50ul","title":"WRN(Phospho Ser1141) Polyclonal Antibody, 50ul","description":"\u003cp\u003eThis gene encodes a member of the RecQ subfamily and the DEAH (Asp-Glu-Ala-His) subfamily of DNA and RNA helicases. DNA helicases are involved in many aspects of DNA metabolism| including transcription| replication| recombination| and repair. This protein contains a nuclear localization signal in the C-terminus and shows a predominant nucleolar localization. It possesses an intrinsic 3' to 5' DNA helicase activity| and is also a 3' to 5' exonuclease. Based on interactions between this protein and Ku70\/80 heterodimer in DNA end processing| this protein may be involved in the repair of double strand DNA breaks. Defects in this gene are the cause of Werner syndrome| an autosomal recessive disorder characterized by premature aging. \u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56514823946613,"sku":"BT-AP01821-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_5.jpg?v=1767678439","url":"https:\/\/www.labcart.com\/de\/products\/wrnphospho-ser1141-polyclonal-antibody-50ul","provider":"LabCart Life Science","version":"1.0","type":"link"}