{"product_id":"zap-70-polyclonal-antibody-50ulbt-ap09645","title":"ZAP-70 Polyclonal Antibody, 50ul[BT-AP09645]","description":"\u003cp\u003eZAP70 (zeta chain of T cell receptor associated protein kinase 70) encodes an enzyme belonging to the protein tyrosine kinase family, and it plays a role in T-cell development and lymphocyte activation. This enzyme, which is phosphorylated on tyrosine residues upon T-cell antigen receptor (TCR) stimulation, functions in the initial step of TCR-mediated signal transduction in combination with the Src family kinases, Lck and Fyn. This enzyme is also essential for thymocyte development. Mutations in ZAP70 cause selective T-cell defect, a severe combined immunodeficiency disease characterized by a selective absence of CD8-positive T-cells. Two transcript variants that encode different isoforms have been found for ZAP70.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56514507506037,"sku":"BT-AP09645-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_6.jpg?v=1768209536","url":"https:\/\/www.labcart.com\/de\/products\/zap-70-polyclonal-antibody-50ulbt-ap09645","provider":"LabCart Life Science","version":"1.0","type":"link"}