{"product_id":"acetyl-lys-proteins-polyclonal-antibody-20ul","title":"Acetyl Lys proteins Polyclonal Antibody, 20ul","description":"\u003cp\u003eAcetylation of lysine| like phosphorylation of serine| threonine or tyrosine| is an important reversible modification controlling protein activity. The conserved amino-terminal domains of the four core histones (H2A| H2B| H3| and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs). Signaling resulting in acetylation\/deacetylation of histones| transcription factors| and other proteins affects a diverse array of cellular processes including chromatin structure and gene activity| cell growth| differentiation| and apoptosis. Recent proteomic surveys suggest that acetylation of lysine residues may be a widespread and important form of posttranslational protein modification that affects thousands of proteins involved in control of cell cycle and metabolism| longevity| actin polymerization| and nuclear transport. The regulation of protein acetylation status is impaired in cancer and polyglutamine diseases| and HDACs have become promising targets for anti-cancer drugs currently in development. \u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56512770474357,"sku":"BT-AP14071-20ul","price":97.2,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon4_b9646263-7fda-4fd2-82e8-9047834a0edb.jpg?v=1767148117","url":"https:\/\/www.labcart.com\/products\/acetyl-lys-proteins-polyclonal-antibody-20ul","provider":"LabCart Life Science","version":"1.0","type":"link"}