{"product_id":"acy1-polyclonal-antibody-50ul","title":"ACY1 Polyclonal Antibody, 50ul","description":"\u003cp\u003eThis gene encodes a cytosolic| homodimeric| zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and an acyl group| and has been postulated to function in the catabolism and salvage of acylated amino acids. This gene is located on chromosome 3p21.1| a region reduced to homozygosity in small-cell lung cancer (SCLC)| and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart| and this enzyme is the first member of a new family of zinc-binding enzymes. Mutations in this gene cause aminoacylase-1 deficiency| a metabolic disorder characterized by central nervous system defects and increased urinary excretion of N-acetylated amino acids. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription als\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56515677782389,"sku":"BT-AP14120-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/acy1-polyclonal-antibody-50ul","provider":"LabCart Life Science","version":"1.0","type":"link"}