{"product_id":"apaf-1-alt-polyclonal-antibody-20ul","title":"Apaf-1-ALT Polyclonal Antibody, 20ul","description":"\u003cp\u003eAPAF1 encodes a cytoplasmic protein that initiates apoptosis. This protein (apoptotic peptidase activating factor 1) contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56507906195829,"sku":"BT-AP00502-20ul","price":97.2,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/apaf-1-alt-polyclonal-antibody-20ul","provider":"LabCart Life Science","version":"1.0","type":"link"}