{"product_id":"bcar3-polyclonal-antibody-20ul","title":"BCAR3 Polyclonal Antibody, 20ul","description":"\u003cp\u003eBreast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. BCAR3 (breast cancer anti-estrogen resistance 3) encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for BCAR3.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56507920679285,"sku":"BT-AP00851-20ul","price":97.2,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/bcar3-polyclonal-antibody-20ul","provider":"LabCart Life Science","version":"1.0","type":"link"}