{"product_id":"bcl-6-acetyl-lys379-rabbit-polyclonal-antibody-50ul","title":"Bcl-6 (Acetyl Lys379) Rabbit Polyclonal Antibody, 50ul","description":"\u003cp\u003edisease:A chromosomal aberration involving BCL6 may be a cause of a form of B-cell leukemia. Translocation t(3;11)(q27;q23) with POU2AF1\/OBF1.|disease:A chromosomal aberration involving BCL6 may be a cause of lymphoma. Translocation t(3;4)(q27;p11) with ARHH\/TTF.|disease:Chromosomal aberrations involving BCL6 may be a cause of B-cell non-Hodgkin lymphoma. Translocation t(3;14)(q27;q32); translocation t(3;22)(q27;q11) with immunoglobulin gene regions.|Transcriptional repressor which is required for germinal center formation and antibody affinity maturation. Probably plays an important role in lymphomagenesis.|induction:Down-regulated during maturation of dendritic cells by selective stimuli such as LPS| CD40L and zymosan.|PTM:Phosphorylated by MAPK1 in response to antigen receptor activation. Phosphorylation induces its degradation by ubiquitin\/proteasome pathway.|Contains 1 BTB (POZ) domain.|Contains 6 C2H2-type zinc fingers.|subunit:Interacts with ZBTB7 and BCL6B (By similarity). Interacts with the catalytic domain of HDAC9.|tissue specificity:Expressed in germinal center T and B cells and in primary immature dendritic cells.|\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56514748612981,"sku":"BT-AP06303-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_6.jpg?v=1768209536","url":"https:\/\/www.labcart.com\/products\/bcl-6-acetyl-lys379-rabbit-polyclonal-antibody-50ul","provider":"LabCart Life Science","version":"1.0","type":"link"}