{"product_id":"bestrophin-1-polyclonal-antibody-100ul","title":"Bestrophin-1 Polyclonal Antibody, 100ul","description":"\u003cp\u003eThis gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56518238011765,"sku":"BT-AP14451-100ul","price":247.5,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_2.jpg?v=1766710711","url":"https:\/\/www.labcart.com\/products\/bestrophin-1-polyclonal-antibody-100ul","provider":"LabCart Life Science","version":"1.0","type":"link"}