{"product_id":"btbd6-polyclonal-antibody-20ul","title":"BTBD6 Polyclonal Antibody, 20ul","description":"\u003cp\u003eBTBD6 (BTB\/POZ domain-containing protein 6), also known as BDPL or lens BTB domain protein, is a 410 amino acid protein that contains one BTB\/POZ domain and is specifically expressed in the lens. The BTB\/POZ domain mediates homomeric and heteromeric POZ-POZ interactions and is common to transcriptional regulators involved in chromatin modeling. In several BTB\/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT\/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this transcriptional repression is attenuated. This suggests that BTBD6 may play a role in transcription regulation in the lens.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56507926282613,"sku":"BT-AP00999-20ul","price":97.2,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/btbd6-polyclonal-antibody-20ul","provider":"LabCart Life Science","version":"1.0","type":"link"}