{"product_id":"cd58-polyclonal-antibody-20ulbt-ap01922","title":"CD58 Polyclonal Antibody, 20ul[BT-AP01922]","description":"\u003cp\u003eF7 encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and\/or factor X to factor Xa. Defects in F7 can cause coagulopathy. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing to generate mature polypeptides.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56507962294645,"sku":"BT-AP01922-20ul","price":97.2,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/cd58-polyclonal-antibody-20ulbt-ap01922","provider":"LabCart Life Science","version":"1.0","type":"link"}