{"product_id":"doc-1-polyclonal-antibody-20ul","title":"DOC-1 Polyclonal Antibody, 20ul","description":"\u003cp\u003eCyclin dependent kinase 2 associated protein 1encoded by CDK2AP1 is a cyclin-dependent kinase 2 (CDK2) -associated protein which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha\/primase and mediate the phosphorylation of the large p180 subunit, which suggests a regulatory role in DNA replication during the S-phase of the cell cycle. This protein also forms a core subunit of the nucleosome remodeling and histone deacetylation (NURD) complex that epigenetically regulates embryonic stem cell differentiation. This gene thus plays a role in both cell-cycle and epigenetic regulation. Alternative splicing results in multiple transcript variants encoding distinct isoforms.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56508040544629,"sku":"BT-AP02689-20ul","price":97.2,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/doc-1-polyclonal-antibody-20ul","provider":"LabCart Life Science","version":"1.0","type":"link"}