{"product_id":"e2a-monoclonal-antibody-100ul","title":"E2A Monoclonal Antibody, 100ul","description":"\u003cp\u003eThis gene encodes a member of the E protein (class I) family of helix-loop-helix transcription factors. E proteins activate transcription by binding to regulatory E-box sequences on target genes as heterodimers or homodimers, and are inhibited by heterodimerization with inhibitor of DNA-binding (class IV) helix-loop-helix proteins. E proteins play a critical role in lymphopoiesis, and the encoded protein is required for B and T lymphocyte development. Deletion of this gene or diminished activity of the encoded protein may play a role in lymphoid malignancies. This gene is also involved in several chromosomal translocations that are associated with lymphoid malignancies including pre-B-cell acute lymphoblastic leukemia (t(1|19), with PBX1), childhood leukemia (t(19|19), with TFPT) and acute leukemia (t(12|19), with ZNF384). Alternatively spliced transcript variants encoding multiple isoforms have bee\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56514587132277,"sku":"BT-MCA0454-100ul","price":270.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_6.jpg?v=1768209536","url":"https:\/\/www.labcart.com\/products\/e2a-monoclonal-antibody-100ul","provider":"LabCart Life Science","version":"1.0","type":"link"}