{"product_id":"faddphospho-ser191-polyclonal-antibody-50ul","title":"FADD(Phospho Ser191) Polyclonal Antibody, 50ul","description":"\u003cp\u003eThe Fas associated via death domain encoded by FADD is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. Through its C-terminal death domain, this protein can be recruited by TNFRSF6\/Fas-receptor, tumor necrosis factor receptor, TNFRSF25, and TNFSF10\/TRAIL-receptor, and thus it participates in the death signaling initiated by these receptors. Interaction of this protein with the receptors unmasks the N-terminal effector domain of this protein, which allows it to recruit caspase-8, and thereby activate the cysteine protease cascade. Knockout studies in mice also suggest the importance of this protein in early T cell development. \u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56514740814197,"sku":"BT-AP06166-50ul","price":162.0,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_6.jpg?v=1768209536","url":"https:\/\/www.labcart.com\/products\/faddphospho-ser191-polyclonal-antibody-50ul","provider":"LabCart Life Science","version":"1.0","type":"link"}