{"product_id":"fnk-polyclonal-antibody-100ul","title":"Fnk Polyclonal Antibody, 100ul","description":"\u003cp\u003eSerine\/threonine-protein kinase PLK3 encoded by PLK3 is a member of the highly conserved polo-like kinase family of serine\/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular localization signal. Polo-like kinases are important regulators of cell cycle progression. This gene has also been implicated in stress responses and double-strand break repair. In human cell lines, this protein is reported to associate with centrosomes in a microtubule-dependent manner, and during mitosis, the protein becomes localized to the mitotic apparatus. Expression of a kinase-defective mutant results in abnormal cell morphology caused by changes in microtubule dynamics and mitotic arrest followed by apoptosis.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56516354343285,"sku":"BT-AP03295-100ul","price":247.5,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_5.jpg?v=1767678439","url":"https:\/\/www.labcart.com\/products\/fnk-polyclonal-antibody-100ul","provider":"LabCart Life Science","version":"1.0","type":"link"}