{"product_id":"frs2-polyclonal-antibody-100ulbt-ap03375","title":"FRS2 Polyclonal Antibody, 100ul[BT-AP03375]","description":"\u003cp\u003eFibroblast growth factor (FGF) receptor substrate 2 (FRS2) has an alternative name as SNT-1, it is an adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. FGF receptor substrates (FRS2 and FRS3) are key adaptor proteins that mediate FGF-FGFR signalling in benign as well as malignant tissue. FRS2 is a 508 amino-acid protein, which is phosphorylated on tyrosine residues. The molecular weight of non-phosphorylated FRS2 is 57-68 kDa, but phosphorylated FRS2 is 80-90 kDa. Phosphorylation of FRS2 is associated with activation of a number of MAP kinases. Allele-specific regulation of FGFR2 mRNA expression with a mildly increased breast cancer risk has been reported.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56516357751157,"sku":"BT-AP03375-100ul","price":247.5,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_5.jpg?v=1767678439","url":"https:\/\/www.labcart.com\/products\/frs2-polyclonal-antibody-100ulbt-ap03375","provider":"LabCart Life Science","version":"1.0","type":"link"}