{"product_id":"gch1-polyclonal-antibody-100ul","title":"GCH1 Polyclonal Antibody, 100ul","description":"\u003cp\u003eThis gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme. \u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56518281265525,"sku":"BT-AP15708-100ul","price":247.5,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/Antibody_main_Dungeon_2.jpg?v=1766710711","url":"https:\/\/www.labcart.com\/products\/gch1-polyclonal-antibody-100ul","provider":"LabCart Life Science","version":"1.0","type":"link"}