{"product_id":"human-adenosine-deaminase-ada-elisa-kit-96t","title":"Human Adenosine Deaminase, ADA ELISA Kit , 96T","description":"\u003cp\u003eCatalyzes the hydrolytic deamination of adenosine and 2-deoxyadenosine (PubMed: 8452534, PubMed: 16670267). Plays an important role in purine metabolism and in adenosine homeostasis. Modulates signaling by extracellular adenosine, and so contributes indirectly to cellular signaling events. Acts as a positive regulator of T-cell coactivation, by binding DPP4 (PubMed: 20959412). Its interaction with DPP4 regulates lymphocyte-epithelial cell adhesion (PubMed: 11772392). Enhances dendritic cell immunogenicity by affecting dendritic cell costimulatory molecule expression and cytokines and chemokines secretion (By similarity). Enhances CD4+ T-cell differentiation and proliferation (PubMed: 20959412). Acts as a positive modulator of adenosine receptors ADORA1 and ADORA2A, by enhancing their ligand affinity via conformational change (PubMed: 23193172). Stimulates plasminogen activation (PubMed: 15016824). Plays a role in male fertility (PubMed: 21919946, PubMed: 26166670). Plays a protective role in early postimplantation embryonic development (By similarity).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592477356405,"sku":"BT-E0777Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/human-adenosine-deaminase-ada-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}