{"product_id":"human-caveolin-1-cav-1-elisa-kit-96t","title":"Human Caveolin-1, CAV-1 ELISA Kit , 96T","description":"\u003cp\u003eMay act as a scaffolding protein within caveolar membranes (PubMed: 11751885). Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Mediates the recruitment of CAVIN proteins (CAVIN1\/2\/3\/4) to the caveolae (PubMed: 19262564). Interacts directly with G-protein alpha subunits and can functionally regulate their activity (By similarity). Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor\/CD3-dependent manner (PubMed: 17287217). Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway (By similarity). Negatively regulates TGFB1-mediated activation of SMAD2\/3 by mediating the internalization of TGFBR1 from membrane rafts leading to its subsequent degradation (PubMed: 25893292).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592487219573,"sku":"BT-E1727Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/human-caveolin-1-cav-1-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}