{"product_id":"human-cgmp-dependent-protein-kinase-2-prkg2-elisa-kit-96t","title":"Human Cgmp-dependent Protein Kinase 2, PRKG2 ELISA Kit , 96T","description":"\u003cp\u003eCrucial regulator of intestinal secretion and bone growth (By similarity). Phosphorylates and activates CFTR on the plasma membrane. Plays a key role in intestinal secretion by regulating cGMP-dependent translocation of CFTR in jejunum (By similarity). Acts downstream of NMDAR to activate the plasma membrane accumulation of GRIA1\/GLUR1 in synapse and increase synaptic plasticity. Phosphorylates GRIA1\/GLUR1 at Ser-863 (By similarity). Acts as regulator of gene expression and activator of the extracellular signal-regulated kinases MAPK3\/ERK1 and MAPK1\/ERK2 in mechanically stimulated osteoblasts. Under fluid shear stress, mediates ERK activation and subsequent induction of FOS, FOSL1\/FRA1, FOSL2\/FRA2 and FOSB that play a key role in the osteoblast anabolic response to mechanical stimulation (By similarity).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592651780469,"sku":"BT-E5035Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/human-cgmp-dependent-protein-kinase-2-prkg2-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}