{"product_id":"human-cytochrome-p450-11b2-mitochondrial-aldos-elisa-kit-96t","title":"Human Cytochrome P450 11B2, Mitochondrial, ALDOS ELISA Kit, 96T","description":"\u003cp\u003eA cytochrome P450 monooxygenase that catalyzes the biosynthesis of adrenal mineralocorticoid aldosterone (PubMed: 11856349, PubMed: 23322723, PubMed: 1594605, PubMed: 9814506). Catalyzes three sequential oxidative reactions of 11-deoxycorticosterone\/21-hydroxyprogesterone, namely 11-beta hydroxylation followed with two successive oxidations at C18 to yield 18-hydroxy and then 18-aldehyde derivatives, resulting in the formation of aldosterone (PubMed: 11856349, PubMed: 23322723, PubMed: 1594605, PubMed: 9814506). Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the second into a water molecule. Two electrons are provided by NADPH via a two-protein mitochondrial transfer system comprising flavoprotein FDXR (adrenodoxin\/ferredoxin reductase) and nonheme iron-sulfur protein FDX1 or FDX2 (adrenodoxin\/ferredoxin) (PubMed: 11856349, PubMed: 23322723, PubMed: 1594605, PubMed: 9814506).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592504127861,"sku":"BT-E2440Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/human-cytochrome-p450-11b2-mitochondrial-aldos-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}