{"product_id":"human-cytochrome-p450-26a1-cyp26a1-elisa-kit-96t","title":"Human Cytochrome P450 26A1, CYP26A1 ELISA Kit, 96T","description":"\u003cp\u003eA cytochrome P450 monooxygenase involved in the metabolism of all-trans retinoic acid (atRA), a signaling molecule that binds to retinoic acid receptors and regulates gene transcription. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase). Catalyzes the hydroxylation of carbon hydrogen bonds of atRA primarily at C-4 and C-18. Has no activity toward 9-cis and 13-cis retinoic acid stereoisomers (PubMed: 22020119, PubMed: 9228017, PubMed: 9716180). May play a role in the oxidative metabolism of xenobiotics such as tazarotenic acid (PubMed: 26937021).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592655057269,"sku":"BT-E5159Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/human-cytochrome-p450-26a1-cyp26a1-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}