{"product_id":"human-integrin-β2-itg-b2-elisa-kit-96t","title":"Human Integrin Β2, ITG B2 ELISA Kit , 96T","description":"\u003cp\u003eIntegrin ITGAL\/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL\/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL (PubMed: 29100055). Integrins ITGAM\/ITGB2 and ITGAX\/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX\/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM\/ITGB2 recognizes P1 and P2 Peptides of fibrinogen gamma chain. Integrin ITGAM\/ITGB2 is also a receptor for factor X. Integrin ITGAD\/ITGB2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity (PubMed: 15356110). Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils (PubMed: 11812992, PubMed: 28807980). Triggers neutrophil transmigration during lung injury through PTK2B\/PYK2-mediated activation (PubMed: 18587400). Integrin ITGAL\/ITGB2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages (PubMed: 23775590). In association with alpha subunit ITGAM\/CD11b, required for CD177-PRTN3-mediated activation of TNF primed neutrophils (PubMed: 21193407).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592470606197,"sku":"BT-E0237Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/human-integrin-%ce%b22-itg-b2-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}