{"product_id":"human-interleukin-33-il-33-elisa-kit-96t","title":"Human Interleukin 33, IL-33 ELISA Kit , 96T","description":"\u003cp\u003eCytokine that binds to and signals through the IL1RL1\/ST2 receptor which in turn activates NF-kappa-B and MAPK signaling pathways in target cells (PubMed: 16286016). Involved in the maturation of Th2 cells inducing the secretion of T-helper type 2-associated cytokines. Also involved in activation of mast cells, basophils, eosinophils and natural killer cells. Acts as a chemoattractant for Th2 cells, and may function as an 'alarmin', that amplifies immune responses during tissue injury (PubMed: 17853410, PubMed: 18836528). In quiescent endothelia the uncleaved form is constitutively and abundantly expressed, and acts as a chromatin-associated nuclear factor with transcriptional repressor properties, it may sequester nuclear NF-kappaB\/RELA, lowering expression of its targets (PubMed: 21734074). This form is rapidely lost upon angiogenic or proinflammatory activation (PubMed: 18787100).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592460480885,"sku":"BT-E0044Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/human-interleukin-33-il-33-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}