{"product_id":"human-kappa-type-opioid-receptor-oprk1-elisa-kit-96t","title":"Human Kappa-type Opioid Receptor, OPRK1 ELISA Kit, 96T","description":"\u003cp\u003eG-protein coupled opioid receptor that functions as receptor for endogenous alpha-neoendorphins and dynorphins, but has low affinity for beta-endorphins. Also functions as receptor for various synthetic opioids and for the psychoactive diterpene salvinorin A. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain. Plays a role in mediating reduced physical activity upon treatment with synthetic opioids. Plays a role in the regulation of salivation in response to synthetic opioids. May play a role in arousal and regulation of autonomic and neuroendocrine functions.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592567697781,"sku":"BT-E4216hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/human-kappa-type-opioid-receptor-oprk1-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}