{"product_id":"human-membrane-co-factor-protein-mcp-elisa-kit-96t","title":"Human Membrane Co Factor Protein, MCP ELISA Kit , 96T","description":"\u003cp\u003eActs as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. (Microbial infection) A number of viral and bacterial pathogens seem to bind MCP in order to exploit its immune regulation property and directly induce an immunosuppressive phenotype in T-cells. (Microbial infection) Acts as a receptor for Adenovirus subgroup B2 and Ad3. (Microbial infection) Acts as a receptor for cultured Measles virus. (Microbial infection) Acts as a receptor for Herpesvirus 6\/HHV-6. (Microbial infection) May act as a receptor for pathogenic bacteria Neisseria and Streptococcus pyogenes (PubMed: 7708671, PubMed: 9379894, PubMed: 11260136, PubMed: 11971006).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592471097717,"sku":"BT-E0275Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/human-membrane-co-factor-protein-mcp-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}