{"product_id":"human-methionine-aminopeptidase-2-metap2-elisa-kit-96t","title":"Human Methionine Aminopeptidase 2, METAP2 ELISA Kit, 96T","description":"\u003cp\u003eCotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). The catalytic activity of human METAP2 toward Met-Val Peptides is consistently two orders of magnitude higher than that of METAP1, suggesting that it is responsible for processing proteins containing N-terminal Met-Val and Met-Thr sequences in vivo. Protects eukaryotic initiation factor EIF2S1 from translation-inhibiting phosphorylation by inhibitory kinases such as EIF2AK2\/PKR and EIF2AK1\/HCR. Plays a critical role in the regulation of protein synthesis.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592542433653,"sku":"BT-E3955Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/human-methionine-aminopeptidase-2-metap2-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}