{"product_id":"human-nicotinamide-phosphoribosyltransferase-nampt-elisa-kit-96t","title":"Human Nicotinamide Phosphoribosyltransferase, NAMPT ELISA Kit, 96T","description":"\u003cp\u003eCatalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, an intermediate in the biosynthesis of NAD. It is the rate limiting component in the mammalian NAD biosynthesis pathway. The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma. Plays a role in the modulation of circadian clock function. NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL\/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592537420149,"sku":"BT-E3660Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/human-nicotinamide-phosphoribosyltransferase-nampt-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}