{"product_id":"human-norrin-ndp-elisa-kit-96t","title":"Human Norrin, NDP ELISA Kit , 96T","description":"\u003cp\u003eActivates the canonical Wnt signaling pathway through FZD4 and LRP5 coreceptor. Plays a central role in retinal vascularization by acting as a ligand for FZD4 that signals via stabilizing beta-catenin (CTNNB1) and activating LEF\/TCF-mediated transcriptional programs. Acts in concert with TSPAN12 to activate FZD4 independently of the Wnt-dependent activation of FZD4, suggesting the existence of a Wnt-independent signaling that also promote accumulation the beta-catenin (CTNNB1). May be involved in a pathway that regulates neural cell differentiation and proliferation. Possible role in neuroectodermal cell-cell interaction.\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592674521461,"sku":"BT-E5788Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/human-norrin-ndp-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}