{"product_id":"human-oxysterol-binding-protein-related-protein-3-osbpl3-elisa-kit-96t","title":"Human Oxysterol-binding Protein-related Protein 3, OSBPL3 ELISA Kit, 96T","description":"\u003cp\u003ePhosphoinositide-binding protein which associates with both cell and endoplasmic reticulum (ER) membranes (PubMed: 16143324). Can bind to the ER membrane protein VAPA and recruit VAPA to plasma membrane sites, thus linking these intracellular compartments (PubMed: 25447204). The ORP3-VAPA complex stimulates RRAS signaling which in turn attenuates integrin beta-1 (ITGB1) activation at the cell surface (PubMed: 18270267, PubMed: 25447204). With VAPA, may regulate ER morphology (PubMed: 16143324). Has a role in regulation of the actin cytoskeleton, cell polarity and cell adhesion (PubMed: 18270267). Binds to phosphoinositides with preference for PI(3,4)P2 and PI(3,4,5)P3 (PubMed: 16143324). Also binds 25-hydroxycholesterol and cholesterol (PubMed: 17428193).\u003c\/p\u003e","brand":"BT LAB","offers":[{"title":"Default Title","offer_id":56592529916277,"sku":"BT-E3359Hu-96T","price":370.98,"currency_code":"EUR","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0843\/2671\/1640\/files\/ELISA_Kit_main_1.jpg?v=1766393459","url":"https:\/\/www.labcart.com\/products\/human-oxysterol-binding-protein-related-protein-3-osbpl3-elisa-kit-96t","provider":"LabCart Life Science","version":"1.0","type":"link"}